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Immune system: Structure, function and influencing factors

The immune system protects our bodies against viruses, bacteria and other foreign substances. This article provides a concise overview of its functions, structure, key influencing factors and the role of selected micronutrients.

Tasks of the immune system

The immune system performs several important protective functions in the body. It detects potentially harmful structures and activates coordinated defence mechanisms.

The core tasks of the immune system include:

  • Detecting pathogens and foreign substances
  • Activation and coordination of specific immune cells
  • Triggering and regulation of inflammatory reactions
  • Breakdown of damaged or infected cells

These processes are ongoing, and they ensure that the body is able to react to pathogens.

Innate immune system

The innate immune system forms the body’s first protective barrier and is already present at birth. It reacts quickly and non-specifically to potential pathogens or other foreign structures.

Its components include, but are not limited to:

  • Skin and mucous membranes as the first barriers
  • Various immune cells
  • Inflammatory reactions as part of the natural defence system

Acquired immune system

The acquired immune system works in a more targeted manner and develops further over the course of our lifetime. It can react specifically to known pathogens.

Specialised immune cells that produce antibodies play an important role in this. These recognise specific pathogen structures and support the targeted fight against pathogens.

 Key points at a glance

  • Protection from pathogens and foreign structures
  • Coordination and control of the immune system response
  • Innate immune defence → fast and non-specific
  • Acquired immune defence → targeted and able to learn

What factors influence the functioning of the immune system?

The normal functioning of the immune system is shaped by several internal and external factors. These include nutrition, lifestyle, seasonal influences as well as age and individual phase of life.

Nutrition

Nutrition has an impact on numerous metabolic processes that are also relevant for immune function. An adequate supply of energy, macro- and micronutrients supports the normal functioning of the immune system.

A large proportion of the immune cells are located in the intestine. The integrity of the intestinal barrier and the composition of the intestinal microbiome are also closely related to the immune system and are influenced by nutrition.

A selection of healthy foods

Lifestyle

Lifestyle factors such as sleep, physical activity and stress can also influence the functioning of the immune system.

For example, getting enough sleep and regular exercise are linked to the normal functioning of the immune system.

Age and phase of life

With increasing age, various physiological functions of the body can change – including immune function. This means that both the activity and the distribution of different immune cells can change over the course of a lifetime.

Certain phases of life, health conditions or medication can also influence the functioning of the immune system.

Seasonal aspects

In the winter months, the immune system is often under greater strain because pathogens are more common.

At the same time, the body’s own production of vitamin D may be reduced due to lower exposure to sunlight. Vitamin D contributes to the normal functioning of the immune system and plays a supporting role.

What role do micronutrients play in the immune system?

Micronutrients are vital substances that the body cannot produce itself or can only produce to a limited extent. They must therefore be ingested regularly through the diet. An adequate supply of certain micronutrients helps the immune system to perform its functions in the body normally.

Micronutrients that contribute to the normal functioning of the immune system include, but are not limited to:

  • Vitamin C
  • Vitamin D
  • Vitamin A or beta-carotene as a precursor to vitamin A
  • Zinc
  • Selenium

The immune system is based on a complex interaction of the innate and acquired immune systems. Its normal function is influenced by many factors, including diet, lifestyle, seasonal conditions and an adequate supply of certain micronutrients.

Focus on the immune system

The immune system is influenced by diet, lifestyle and selected micronutrients. Discover suitable support options.

 

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